A surgical instrument called the Approximator Clamp Frame 1.0-2.25mm was created especially to work with small-to-medium-sized arteries and blood vessels, which normally have a diameter of 1.0 to 2.25mm. When the surgeon wants to approach (bring together) the edges of an artery or blood vessel during procedures like anastomosis, vascular repair, or arterial grafting, it is mostly utilized in vascular surgery, microsurgery, and cardiac surgery.